Scientific Research

Cell-to-cell communication is ubiquitous in the majority of cells and is indispensable for proper development of most tissues. 

Tissue engineering has emerged as a potential alternative or complementary solution to organ failure or damage.

We have cultured 3 lines of cells from different mouse strains that have been shown to be naive or primed as determined by generating germline-transmitting chimeras. Cells were put through a battery of tests to measure the different features.

Pluripotent stem cells are undifferentiated cells that have the potential to become any cell type in the adult body. They have two main hallmarks. First, unlike differentiated somatic cells, stem cells have the ability to self-renew and proliferate.

Gap junction intercellular communication (GJIC) is ubiquitous in the majority of vertebrate cells and is required for the proper development of most tissues. 

Gap junction intercellular communication (GJIC) is ubiquitous in the majority of cells and is indispensable for proper development and function of most tissues. The loss of gap junction mediated cell to cell communication leads to compromised development in many...

Defects in craniofacial tissues, resulting from trauma, congenital abnormalities, oncologic resection or progressive deforming diseases, may result in aesthetic deformity, pain and reduced function.

The bone diagnostic instrument (BDI) is being developed with the long-term goal of providing a way for researchers and clinicians to measure bone material properties of human bone in vivo. Such measurements could contribute to the overall assessment of bone fragility...

Cells are fundamental units of life, but little is known about evolution of cell states.